Granddaughter and grandniece of konoha's first and second hokage I don't see any reason tsunade could beat him, as she specializes in brute strength, not what'd take to beat itachi Ultimate ninja storm 2 on the playstation 3, a gamefaqs q&a question titled pen repair materials for tsunade's quest?.
Tsunade | All Worlds Alliance Wiki | Fandom
Tsunade's fighting style is completely different from gaara, so there is no way you can apply that scaling method
The search for tsunade arc is the fifth arc of the series
With the death of the third hokage, naruto joins jiraiya on the search of the one who shall take his place as hokage, but does she even.
