However, significant involvement of oral, nasal, eye, vaginal, urethral, gastrointestinal, and lower respiratory tract mucous membranes may develop during the illness. * asterisk denotes high number of cases reported antibiotics sulfa based drugs * bactrim * septra * penicillin amoxicillin azithromycin erythromycin ciprofloxin anticonvulsants lamotrigine * tegretol dilantin phenobarbital valproic acid phenytoin carbamazepine barbituates cocaine. Given the grave implications of misdiagnosis, there should be a high index of clinical suspicion for sjs when a patient presents with the constellation of high fever (>102.2), malaise, arthralgia, a macular rash involving the trunk, neck and face, and recent history of new medication exposure or.
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