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You can have genetic abnormalities such as t (4;14) with any stage of a monoclonal gammopathy (mgus, smoldering multiple myeloma or symptomatic multiple myeloma). But it's only one risk factor, and, of course, each's person's disease is unique.

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The free light chain (flc) ratio at diagnosis can be a factor which increases risk of progression at diagnosis My wife has igm myeloma, which is a rare case as i understand I am mgus iga lambda and.

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Didn't do we'll on biphosphates (jaw and dental issues) and my endo dr said i could be a candidate for another bone building drug that has steroids or hormones which could mask an m spike.

There are different models for risk of mgus progression out there from the mayo clinic, pethema, etc

Mgus with forehead lesion & collarbone bone growth by multibilly on wed oct 22, 2014 12:46 pm tennispro, Hello, last thursday i was diagnosed with smoldering myeloma I was diagnosed with smoldering mgus in mid 2013 By jan 2014 it became active and i did six months of chemo, then a stem cell harvest (no transplant)

I tried revlimid as a mainΒ­teΒ­nance therapy but could not tolerate it Hi, my mum was given a diagnosis of mgus over 15 years ago and has had regular bloods and yearly bone marrow biopsies Interesting to hear about the relation between igm and neuropathy

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